公开(公告)号：US20200206222A1

公开(公告)日：2020-07-02

申请号：US16717080

申请日：2019-12-17

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Dominic REYNOLDS ,  Ming-Hong HAO ,  John WANG ,  Sudeep PRAJAPATI ,  Takashi SATOH ,  Anand SELVARAJ

IPC: A61K31/505 ,  A61K31/5377 ,  A61K31/506

Abstract: Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.

公开(公告)号：US20170360785A1

公开(公告)日：2017-12-21

申请号：US15627851

申请日：2017-06-20

Applicant: EISAI R&D MANAGEMENT CO., LTD.

Inventor： Dominic REYNOLDS ,  Ming-Hong HAO ,  John WANG ,  Sudeep PRAJAPATI ,  Takashi SATOH ,  Anand SELVARAJ

IPC: A61K31/505 ,  C07D405/12 ,  C07D403/12 ,  C07D401/12 ,  C07D239/48 ,  C07C53/18 ,  A61K31/5377 ,  C07D413/12 ,  A61K31/506

Abstract: Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.

公开(公告)号：US20170007601A1

公开(公告)日：2017-01-12

申请号：US15221018

申请日：2016-07-27

Applicant: EISAI R&D MANAGEMENT CO., LTD.

Inventor： Dominic REYNOLDS ,  Ming-Hong HAO ,  John WANG ,  Sudeep PRAJAPATI ,  Takashi SATOH ,  Anand SELVARAJ

IPC: A61K31/505 ,  A61K31/5377 ,  G01N33/574 ,  A61K31/506

CPC classification number: A61K31/505 ,  A61K31/506 ,  A61K31/5377 ,  C07C53/18 ,  C07D239/48 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12

Abstract: Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.

Abstract translation: 本文提供了可用作FGFR4抑制剂的式I化合物，以及其用途的方法。