公开(公告)号：US20220023275A1

公开(公告)日：2022-01-27

申请号：US17312077

申请日：2019-12-16

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Geoffrey S. HIRD ,  Ganesh S.P. BOMMAREDDY ,  Anjali JOSHI, Ph.D. ,  James MCSHANE

IPC: A61K31/444 ,  A61K47/40 ,  A61K9/19 ,  A61K9/08

Abstract: An aqueous pharmaceutical formulation of a solubilizing agent with a pyridone compound that is useful as an inhibitor to non-NMDA receptors, particularly to the AMPA receptor is disclosed herein. In some embodiments the pyridone compound is supersaturated in aqueous solution at pH between 6 and 8. The formulations are particularly useful as intravenous injections.