公开(公告)号：US20230062861A1

公开(公告)日：2023-03-02

申请号：US17521666

申请日：2021-11-08

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Sudeep PRAJAPATI ,  Hyelee LEE ,  Stephanos IOANNIDIS ,  Kiyoyuki OMOTO ,  Alan ROLFE ,  Xiang LIU ,  Megan SHEEHAN ,  Paul DRANSFIELD ,  Andrew COOK

IPC: C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D471/04 ,  C07D471/08 ,  C07D493/08 ,  C07D417/14 ,  C07D491/04 ,  C07D409/14 ,  C07D498/08 ,  C07D498/04 ,  C07D487/04 ,  C07D491/10 ,  C07F5/02

Abstract: Disclosed herein are novel compounds of Formula (1) and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing the same, and methods of using the same.

公开(公告)号：US20230026271A1

公开(公告)日：2023-01-26

申请号：US17778635

申请日：2020-11-20

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Alan ROLFE ,  David BOLDUC ,  Nicholas LARSEN ,  Andrew S. COOK ,  Kiyoyuki OMOTO

IPC: C07D241/04 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06

Abstract: We provide compounds that may be useful as CPS1 inhibitors. These compounds may be useful, for example, in the treatment of cancer.