-
公开(公告)号:US09790280B2
公开(公告)日:2017-10-17
申请号:US14354280
申请日:2012-10-25
发明人: Sarah Rue , Brendan Eckelman , Quinn Deveraux , Marc Nasoff
IPC分类号: C07K16/30 , C07K16/28 , A61K39/395 , G01N33/574 , A61K45/06
CPC分类号: C07K16/2887 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/2896 , C07K16/3061 , C07K2317/20 , C07K2317/24 , C07K2317/33 , C07K2317/52 , C07K2317/56 , C07K2317/92 , G01N33/57426
摘要: This disclosure relates to immunogens and monoclonal antibodies useful in the identification and/or treatment of cancer cells, including those of the dog. In one example, chimeric anti-canine CD20 antibodies are provided. The antibodies can be used therapeutically to treat lymphoma in dogs.