公开(公告)号：US20230220589A1

公开(公告)日：2023-07-13

申请号：US17539033

申请日：2021-09-29

申请人： Encodia, Inc.

发明人： Kevin L. GUNDERSON ,  Soumya GANGULY ,  Robert C. JAMES ,  Kenneth KUHN ,  Zachary MILES ,  Lei SHI ,  Stephen VERESPY, III ,  Aaron WISE ,  Zongxiang ZHOU

IPC分类号： C40B40/10

CPC分类号： C40B40/10

摘要： The present disclosure relates to a binder that specifically binds to an N-terminally modified polypeptide through interaction with a modified N-terminal amino acid. Also provided herein is a method and related kits for treating a polypeptide using or comprising the binder and/or modified cleavase. In some embodiments, also provided herein is a method and related kits for transferring information using a plurality of enzymes, including for performing a ligation, extension, and cleavage reaction with nucleic acid molecules associated with the polypeptide for analysis.