公开(公告)号：US20200345690A1

公开(公告)日：2020-11-05

申请号：US16960444

申请日：2019-01-08

Applicant: EpicentRx Inc.

Inventor： Bryan T. ORONSKY ,  Amold ORONSKY ,  Tony R. REID

IPC: A61K31/397

Abstract: Provided herein are therapeutic methods, kits, and pharmaceutical compositions for protecting a subject from radiation using a therapeutic agent selected from the group consisting of RRx-OO1 and a pharmaceutically acceptable salt thereof. One exemplary therapeutic method involves administering RRx-OO1 to the subject prior to the subject being exposed to the radiation, in order to protect the subject against radiation, such as ionizing radiation containing α-rays, β-rays, γ-rays, neutron radiation, or a combination thereof.

公开(公告)号：US20200345689A1

公开(公告)日：2020-11-05

申请号：US16960443

申请日：2019-01-08

Applicant: EpicentRx, Inc.

Inventor： Bryan T. ORONSKY ,  Amold ORONSKY

IPC: A61K31/397 ,  A61K9/00 ,  A61K31/616 ,  A61K45/06 ,  A61K31/196 ,  A61K31/517 ,  A61K33/00 ,  A61N5/10 ,  A61N5/06 ,  A61P39/00

Abstract: Provided herein are therapeutic methods, kits, and pharmaceutical compositions for protecting a subject from radiation using a therapeutic agent selected from the group consisting of RRx-001 and a pharmaceutically acceptable salt thereof. One exemplary therapeutic method involves administering RRx-001 to the subject prior to the subject being exposed to the radiation, in order to protect the subject against radiation, such as ionizing radiation containing α-rays, β-rays, γ-rays, neutron radiation, or a combination thereof.