公开(公告)号：US07863463B2

公开(公告)日：2011-01-04

申请号：US11286190

申请日：2005-11-22

申请人： Eric James Pressman ,  Albert Santo Stella ,  Beatriz Peñalver Bernabe ,  Lioba Maria Kloppenburg ,  Lee Harris Bergman

发明人： Eric James Pressman ,  Albert Santo Stella ,  Beatriz Peñalver Bernabe ,  Lioba Maria Kloppenburg ,  Lee Harris Bergman

IPC分类号： C07D307/77

CPC分类号： C07D307/89

摘要： Disclosed herein is a method for purification of dianhydrides comprising a substantial amount (10000 ppm or more) of at least one metal salt. In one aspect the method is useful for the purification of dianhydrides prepared by the reaction of a halophthalic anhydride with a metal carbonate and may be optionally catalyzed by a phase transfer catalyst. The purification of the dianhydrides may be accomplished by hydrolyzing the dianhydride metal salt mixture directly to a tetraacid with an inorganic acid, followed by separating the impurities from an aqueous phase, and subsequently heating the tetraacid to effect ring closure to form a purified dianhydride having less than 50 parts per million metal halide and lower levels of other residual impurities. In one aspect the method is highly effective in removing phase transfer catalyst impurities such as hexalkylguanidinium halides initially present in the dianhydride undergoing purification.

摘要翻译： 本文公开了包含大量（10000ppm或更多）至少一种金属盐的二酸酐的纯化方法。 在一个方面，该方法可用于纯化通过卤代邻苯二甲酸酐与金属碳酸盐的反应制备的二酐，并且可任选地通过相转移催化剂催化。 二酸酐的纯化可以通过用无机酸将二酐金属盐混合物直接水解成四元酸，然后从水相中分离出杂质，随后加热四酸以实现闭环以形成具有较少量的纯化二酐 超过50ppm的金属卤化物和较低水平的其他残留杂质。 在一个方面，该方法在除去最初存在于经过纯化的二酐中的相转移催化剂杂质如六烷基卤化镓中是非常有效的。