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    TREATMENT OF BIPOLAR DISORDERS AND ASSOCIATED SYMPTOMS
    1.
    发明申请
    TREATMENT OF BIPOLAR DISORDERS AND ASSOCIATED SYMPTOMS 审中-公开
    治疗双肺障碍及相关症状

    公开(公告)号：US20090176855A1

    公开(公告)日：2009-07-09

    申请号：US12405689

    申请日：2009-03-17

    申请人： Erik Ho Fong Wong ,  John Panagides ,  Jacques Schipper

    发明人： Erik Ho Fong Wong ,  John Panagides ,  Jacques Schipper

    IPC分类号： A61K31/407 ,  A61P25/18

    CPC分类号： A61K31/407

    摘要： The present invention relates to a method and kits for treating bipolar disorder in a mammal, including a human, the treatments including treatment of bipolar disorder including rapid-cycling, treatment of symptoms of bipolar disorder including acute mania or hypomania and depression, and episodes or occurrences including both acute mania or hypomania and depression; treatment for effecting mood stabilization; treatment for preventing relapse into bipolar episodes, and for the treatment of suicidal thoughts and tendencies associated with bipolar disorder, comprising administering to said mammal an effective amount of a compound of Formula or a pharmaceutically acceptable salt, solvate, hydrate or optical isomer thereof.

    摘要翻译： 本发明涉及用于治疗哺乳动物（包括人）的双相性精神障碍的方法和试剂盒，包括治疗包括快速循环，包括急性躁狂症或轻度躁动症和抑郁症的双相情感障碍症状的治疗双相障碍的治疗，以及发作或 包括急性躁狂或轻躁狂和抑郁症; 治疗情绪稳定; 包括给予所述哺乳动物有效量的式的化合物或其药学上可接受的盐，溶剂合物，水合物或旋光异构体。

    Treatment of bipolar disorders and associated symptoms
    2.
    发明申请
    Treatment of bipolar disorders and associated symptoms 审中-公开
    治疗双相障碍及相关症状

    公开(公告)号：US20060084692A1

    公开(公告)日：2006-04-20

    申请号：US11247342

    申请日：2005-10-11

    申请人： Fong Erik Wong ,  John Panagides ,  Jacques Schipper

    发明人： Fong Erik Wong ,  John Panagides ,  Jacques Schipper

    IPC分类号： A61K31/407

    CPC分类号： A61K31/407

    摘要： The present invention relates to a method and kits for treating bipolar disorder in a mammal, including a human, the treatments including treatment of bipolar disorder including rapid-cycling, treatment of symptoms of bipolar disorder including acute mania or hypomania and depression, and episodes or occurrences including both acute mania or hypomania and depression; treatment for effecting mood stabilization; treatment for preventing relapse into bipolar episodes, and for the treatment of suicidal thoughts and tendencies associated with bipolar disorder, comprising administering to said mammal an effective amount of a compound of Formula or a pharmaceutically acceptable salt, solvate, hydrate or optical isomer thereof.

    摘要翻译： 本发明涉及用于治疗哺乳动物（包括人）的双相性精神障碍的方法和试剂盒，包括治疗包括快速循环，包括急性躁狂症或轻度躁动症和抑郁症的双相情感障碍症状的治疗双相障碍的治疗，以及发作或 包括急性躁狂或轻躁狂和抑郁症; 治疗情绪稳定; 包括给予所述哺乳动物有效量的式的化合物或其药学上可接受的盐，溶剂合物，水合物或旋光异构体。

    METHOD OF HORMONE SUPPRESSION IN HUMANS
    3.
    发明申请
    METHOD OF HORMONE SUPPRESSION IN HUMANS 审中-公开
    人体抑制人血红蛋白的方法

    公开(公告)号：US20110118353A1

    公开(公告)日：2011-05-19

    申请号：US12740716

    申请日：2008-11-04

    申请人： Robert Gerard Jules Marie Hanssen ,  Jacques Schipper ,  Josephus Hubertus Schoemaker

    发明人： Robert Gerard Jules Marie Hanssen ,  Jacques Schipper ,  Josephus Hubertus Schoemaker

    IPC分类号： A61K31/198 ,  C07C229/36 ,  A61P5/26 ,  A61P5/30 ,  A61P5/24 ,  A61P15/00

    CPC分类号： A61K31/198

    摘要： The present invention relates to a glycine transporter-1 inhibitor having the formula (I) wherein X is 1-3 substituents selected from H, halogen, methyl, methoxy, trifluoromethyl and trifluoromethoxy and Y is 1-3 substituents selected from H, methyl and halogen or a pharmaceutically acceptable salt thereof for use in a treatment in humans to suppress the level of one or more hormone selected from luteinizing hormone, follicle-stimulating hormone, estradiol and testosterone. The present invention further relates to such a glycine transporter-1 inhibitor as part of a contraceptive regimen or as a treatment for hypersexuality.

    摘要翻译： 本发明涉及具有式（I）的甘氨酸转运蛋白-1抑制剂，其中X是1-3个选自H，卤素，甲基，甲氧基，三氟甲基和三氟甲氧基的取代基，Y是1-3个选自H，甲基和 卤素或其药学上可接受的盐，用于人类的治疗以抑制选自黄体生成激素，促卵泡激素，雌二醇和睾酮的一种或多种激素的水平。 本发明还涉及作为避孕方案的一部分的甘氨酸转运蛋白-1抑制剂或作为超嗜性的治疗剂。