公开(公告)号：US08460889B2

公开(公告)日：2013-06-11

申请号：US13543745

申请日：2012-07-06

申请人： Jay W. Heinecke ,  Tomas Vaisar ,  Bryan Prazen ,  Erik Nilsson

发明人： Jay W. Heinecke ,  Tomas Vaisar ,  Bryan Prazen ,  Erik Nilsson

IPC分类号： G01N33/53 ,  G01N31/00

CPC分类号： G01N33/92 ,  G01N2333/775 ,  G01N2800/32

摘要： The invention provides methods of screening a mammalian subject to determine if the subject is at risk to develop or is suffering from, cardiovascular disease. In one embodiment, the method comprises detecting a measurable feature of at least two biomarkers in an HDL subfraction, or in a complex containing apoA-I or apoA-III isolated from a biological sample obtained from the subject, wherein the at least two biomarkers are selected from the group consisting of apoA-I, apoA-II, apoB-100, Lp(a), apoC-I, and apoC-III, combinations or portions and/or derivatives thereof, and comparing the measurable features of the at least two biomarkers from the biological sample to a reference standard, wherein a difference in the measurable features of the at least two biomarkers from the biological sample and the reference standard is indicative of the presence or risk of cardiovascular disease in the subject.

摘要翻译： 本发明提供筛选哺乳动物受试者以确定受试者是否处于发展或正在患有心血管疾病的风险中的方法。 在一个实施方案中，所述方法包括检测HDL亚分级中的至少两个生物标志物的可测量特征，或在从所述受试者获得的生物样品中分离的含有apoA-I或apoA-III的复合物中，其中所述至少两种生物标志物是 选自由apoA-I，apoA-II，apoB-100，Lp（a），apoC-1和apoC-III组成的组，其组合或部分和/或衍生物，并将至少可测量特征 来自生物样品的两个生物标志物到参考标准，其中来自生物样品和参考标准的至少两种生物标志物的可测量特征的差异指示受试者心血管疾病的存在或风险。

公开(公告)号：US20130036064A1

公开(公告)日：2013-02-07

申请号：US13196280

申请日：2011-08-02

申请人： John Osvald ,  Michael Waite ,  Kyle Sauger ,  Lauren Duncan ,  Erik Nilsson

发明人： John Osvald ,  Michael Waite ,  Kyle Sauger ,  Lauren Duncan ,  Erik Nilsson

IPC分类号： G06Q99/00

CPC分类号： G06Q30/0209 ,  G06Q20/06 ,  G07F17/32

摘要： Methods, systems, and computer programs for generating revenue in an online game are presented. One method includes an operation for creating, in the online game, a first virtual currency and a game score, where the amount of the first virtual currency can be increased in exchange for real currency. The first virtual currency can be traded for advancement in the online game. Further, a game module, that is an autonomous game within the online game, is started, and a second virtual currency and a module score are created in the game module. The amount of the second virtual currency can be increased in exchange for real currency, where the second virtual currency can be traded for advancement in the game module and cannot be traded for advancement in the online game outside of the game module. Advancement in the game module increases the module score and does not increase the game score. In addition, at least one form of advancement in the game module can be obtained with the second virtual currency and cannot be obtained with the first virtual currency.

摘要翻译： 介绍了在网络游戏中创造收入的方法，系统和计算机程序。 一种方法包括用于在在线游戏中创建第一虚拟货币和游戏得分的操作，其中可以增加第一虚拟货币的数量以换取实际货币。 第一个虚拟货币可以在网络游戏中进行交易。 此外，开始在线游戏内的自主游戏的游戏模块，并且在游戏模块中创建第二虚拟币种和模块得分。 可以增加第二虚拟货币的数量以兑换实际货币，其中第二虚拟货币可以在游戏模块中进行交易，并且不能在游戏模块之外的在线游戏中进行交易。 游戏模块的进步增加了模块得分，并没有增加游戏得分。 此外，可以利用第二虚拟货币获得游戏模块中的至少一种进步形式，并且不能用第一虚拟货币获得。

公开(公告)号：US20120288880A1

公开(公告)日：2012-11-15

申请号：US13543745

申请日：2012-07-06

申请人： Jay W. Heinecke ,  Tomas Vaisar ,  Bryan Prazen ,  Erik Nilsson

发明人： Jay W. Heinecke ,  Tomas Vaisar ,  Bryan Prazen ,  Erik Nilsson

IPC分类号： H01J49/26 ,  G01N33/53

CPC分类号： G01N33/92 ,  G01N2333/775 ,  G01N2800/32

摘要： The invention provides methods of screening a mammalian subject to determine if the subject is at risk to develop or is suffering from, cardiovascular disease. In one embodiment, the method comprises detecting a measurable feature of at least two biomarkers in an EMT subfraction, or in a complex containing apoA-I or apoA-III isolated from a biological sample obtained from the subject, wherein the at least two biomarkers are selected from the group consisting of apoA-I, apoA-II, apoB-100, Lp(a), apoC-I, and apoC-III, combinations or portions and/or derivatives thereof, and comparing the measurable features of the at least two biomarkers from the biological sample to a reference standard, wherein a difference in the measurable features of the at least two biomarkers from the biological sample and the reference standard is indicative of the presence or risk of cardiovascular disease in the subject.

摘要翻译： 本发明提供筛选哺乳动物受试者以确定受试者是否处于发展或正在患有心血管疾病的风险中的方法。 在一个实施方案中，所述方法包括检测EMT亚分级中的至少两个生物标志物的可测量特征，或在从受试者获得的生物样品中分离的含有载脂蛋白A-I或载脂蛋白-A-apo的复合物中，其中所述至少两种生物标志物是 选自由apoA-I，apoA-II，apoB-100，Lp（a），apoC-1和apoC-III组成的组，其组合或部分和/或衍生物，并将至少 来自生物样品的两个生物标志物到参考标准，其中来自生物样品和参考标准的至少两种生物标志物的可测量特征的差异指示受试者心血管疾病的存在或风险。

公开(公告)号：US07878363B2

公开(公告)日：2011-02-01

申请号：US10587378

申请日：2005-02-02

申请人： Erik Nilsson

发明人： Erik Nilsson

IPC分类号： A47G19/22 ,  B65D85/62

CPC分类号： B65D1/0238 ,  B65D1/023 ,  B65D41/16 ,  B65D77/28

摘要： A beverage packaging unit (1) that includes an opening (8) from which the liquid contents of the unit can be drunk, wherewith said opening, or orifice (8), can be closed with the aid of an closure element (3). The invention is characterized in that the packaging unit (1) is parallelepipedic in shape including a hollow box-like body (2) and said closer element (3); in that said parallelepipedic hollow box-like body (2) has a bevelled corner at which there is formed a three-sided or triangular surface (7) that connects with said box-like body; in that there projects out from said surface (7) a tubular part (4) that includes said opening or orifice; in that said closure element (3) includes a generally pyamidal body which is shaped so that when in abutment with said bevelled corner of said box-like body (2) it forms, together with said body, said parallelepipedic packaging unit (1); in that said closure element includes a cavity (6) for receiving said tubular part (4); and in that the packaging unit includes co-acting fasteners (10) on said tubular part (4) and also in said cavity (6) for removably retaining said closure element (3) at said tubular part, so that said box-like body (2) and said closure element (3) will form a parallelepiped.

摘要翻译： 一种饮料包装单元（1），其包括开口（8），所述单元的液体内容物可以从所述开口（8）排出，所述开口或孔口（8）可借助于封闭元件（3）封闭。 本发明的特征在于，包装单元（1）的形状为平行六面体形，包括中空盒状体（2）和所述更近的元件（3）; 因为所述平行六面体中空盒状体（2）具有倾斜的角部，在该角部处形成有与所述盒状体连接的三面或三角形表面（7） 其中从所述表面（7）突出出包括所述开口或孔口的管状部分（4）; 因为所述封闭元件（3）包括大体上具有夹角的主体，该主体的形状使得当与所述盒状主体（2）的所述倾斜角部邻接时，其与所述主体一起形成所述平行六面体包装单元（1）; 因为所述封闭元件包括用于接收所述管状部分（4）的空腔（6）。 并且所述包装单元包括在所述管状部件（4）上并且还在所述空腔（6）中的共同作用的紧固件（10），用于将所述封闭元件（3）可移除地保持在所述管状部分处，使得所述盒状体 （2）和所述封闭元件（3）将形成平行六面体。

公开(公告)号：US20070005254A1

公开(公告)日：2007-01-04

申请号：US10574382

申请日：2005-04-02

申请人： Erik Nilsson ,  Brian Pratt

发明人： Erik Nilsson ,  Brian Pratt

IPC分类号： G06F19/00

CPC分类号： G01N30/8651 ,  G01N30/463

摘要： Methods and apparatuses are described to process an n-dimensional data set acquired from a measurement on a biological sample. A method includes dividing an n-dimensional data set into n-dimensional sub-regions, wherein a size of a dimension of an n-dimensional sub-region is less than a size of the dimension of the n-dimensional data set. The n-dimensional sub-regions are stored on a computer readable medium and the computer readable medium is accessible to a data processing system. The n-dimensional data set can exceed an addressable memory limit of the data processing system and mathematical operations are performed on the n-dimensional data set.

摘要翻译： 描述了用于处理从生物样品上的测量获取的n维数据集的方法和装置。 一种方法包括将n维数据集划分为n维子区域，其中n维子区域的维度的大小小于n维数据集的维度的大小。 n维子区域存储在计算机可读介质上，并且计算机可读介质可被数据处理系统访问。 n维数据集可以超过数据处理系统的可寻址存储器限制，并且对n维数据集执行数学运算。

公开(公告)号：US06325891B1

公开(公告)日：2001-12-04

申请号：US08553324

申请日：1995-11-20

申请人： Anders Bergqvist ,  Lars Ove Larsson ,  Erik Nilsson ,  Petter Tibbling

发明人： Anders Bergqvist ,  Lars Ove Larsson ,  Erik Nilsson ,  Petter Tibbling

IPC分类号： D21C9153

摘要： Provided is a method of treating chemical paper pulp having the steps of: adjusting the pH of the pulp to be between 1 and 6; treating the pulp with ozone to reduce the kappa number of the pulp; treating the pulp with a chelating agent after the ozone treating step without any intervening washing step between the ozone treating step and the chelating agent treating step; adjusting the pH of the pulp by adding alkali together with or after the addition of chelating agent to a pH exceeding 3; washing the pulp; and bleaching the pulp with peroxide.

摘要翻译： 提供了一种处理化学纸浆的方法，其具有以下步骤：将纸浆的pH调节至1至6;用臭氧处理纸浆以降低纸浆的卡伯值;处理纸浆后的螯合剂 臭氧处理步骤，在臭氧处理步骤和螯合剂处理步骤之间没有任何中间的洗涤步骤;通过在加入螯合剂或加入螯合剂之后加入碱调节浆液的pH至pH超过3;洗涤纸浆; 并用过氧化物漂白纸浆。

公开(公告)号：US10086292B2

公开(公告)日：2018-10-02

申请号：US13196846

申请日：2011-08-02

申请人： John Osvald ,  Michael Waite ,  Kyle Sauger ,  Lauren Duncan ,  Erik Nilsson

发明人： John Osvald ,  Michael Waite ,  Kyle Sauger ,  Lauren Duncan ,  Erik Nilsson

IPC分类号： A63F13/795 ,  A63F13/655

摘要： A method for performing a social project in a video game is provided. A session of the video game for a primary user is initiated, and a social project is initiated within the session of the video game. One or more secondary users are determined from a social graph of the primary user. A message requesting help to complete the social project is sent to the one or more secondary users, the message including a low-friction response mechanism. Upon activation of the low-friction response mechanism of the request, a response is received indicating an intent to help complete the social project from a responsive secondary user. Upon receiving the response, automated retrieval and animation of an avatar of the responsive secondary user is triggered within the primary user's session of the video game so as to collaborate on the social project.

公开(公告)号：US07926673B2

公开(公告)日：2011-04-19

申请号：US12293086

申请日：2007-03-06

申请人： Erik Nilsson

发明人： Erik Nilsson

IPC分类号： B65D51/20

CPC分类号： B65D1/0223 ,  B65D47/08 ,  B65D2501/0081

摘要： Beverage package container includes an opening, which is resealable using a sealing device, where the package container is essentially or completely parallelepipedic, including a hollow, box-shaped body and the sealing device, where a corner of the parallelepipedic, hollow, box-shaped body is chamfered, at which corner a triangular surface is formed, connecting to the box-shaped body, where a tube-shaped part extends out from the surface, including the opening. The sealing device has an essentially pyramid-shaped body, designed so that it, together with the body, forms the parallelepipedic package container when it bears on the triangular surface of the box-shaped body, and a cavity for receiving the tube-shaped part, and where cooperating members are arranged, on the tube-shaped part as well as in the cavity, for removably and tight-fittingly detaining the sealing device at the tube-shaped part, so that the box-shaped body and the sealing device together form a parallelepiped.

摘要翻译： 饮料包装容器包括可使用密封装置重新密封的开口，其中包装容器基本上或完全平行六面体，包括中空的箱形主体和密封装置，其中平行六面体，中空，箱形 主体被倒角，在该角部处形成三角形表面，连接到箱形体，其中管状部分从包括开口的表面延伸出来。 密封装置具有基本上金字塔形的主体，其被设计成使其与主体一起形成平行六面体包装容器，当其支撑在箱形体的三角形表面上时，以及用于容纳管状部分的空腔 ，并且配合构件配置在管状部以及空腔中，用于可拆卸地且紧密地将密封装置保持在管状部分处，使得箱形体和密封装置在一起 形成平行六面体

公开(公告)号：US20090045200A1

公开(公告)日：2009-02-19

申请号：US12293086

申请日：2007-03-06

申请人： Erik Nilsson

发明人： Erik Nilsson

IPC分类号： B65D39/14 ,  B65D39/08 ,  A47G19/22

CPC分类号： B65D1/0223 ,  B65D47/08 ,  B65D2501/0081

摘要： Beverage package container includes an opening, which is resealable using a sealing device, where the package container is essentially or completely parallelepipedic, including a hollow, box-shaped body and the sealing device, where a corner of the parallelepipedic, hollow, box-shaped body is chamfered, at which corner a triangular surface is formed, connecting to the box-shaped body, where a tube-shaped part extends out from the surface, including the opening. The sealing device has an essentially pyramid-shaped body, designed so that it, together with the body, forms the parallelepipedic package container when it bears on the triangular surface of the box-shaped body, and a cavity for receiving the tube-shaped part, and where cooperating members are arranged, on the tube-shaped part as well as in the cavity, for removably and tight-fittingly detaining the sealing device at the tube-shaped part, so that the box-shaped body and the sealing device together form a parallelepiped.

摘要翻译： 饮料包装容器包括可使用密封装置重新密封的开口，其中包装容器基本上或完全平行六面体，包括中空的箱形主体和密封装置，其中平行六面体，中空，箱形 主体被倒角，在该角部处形成三角形表面，连接到箱形体，其中管状部分从包括开口的表面延伸出来。 密封装置具有基本上金字塔形的主体，其被设计成使其与主体一起形成平行六面体包装容器，当其支撑在箱形体的三角形表面上时，以及用于容纳管状部分的空腔 ，并且配合构件配置在管状部以及空腔中，用于可拆卸地且紧密地将密封装置保持在管状部分处，使得箱形体和密封装置在一起 形成平行六面体

公开(公告)号：US20070278238A1

公开(公告)日：2007-12-06

申请号：US10587377

申请日：2005-02-02

申请人： Erik Nilsson

发明人： Erik Nilsson

IPC分类号： B65D5/72

CPC分类号： B65D21/0209 ,  B65D1/0223 ,  B65D47/265 ,  B65D2501/0081

摘要： A beverage packaging unit that includes an opening through which a beverage can be drunk or poured, wherein the opening is sealable by a closure element. The packaging unit is parallelepipedal and includes a hollow, box-like body and the closure element. The box-like body has a bevelled corner at which there is formed a triangular surface that is connected with the body. A tubular part extends outwardly from the triangular surface and includes the opening. The closure element includes a generally pyramidal body that is so shaped that when it is in abutment with the bevelled corner of the box-like body it forms, together with the body, the parallelepipedal packaging unit.

摘要翻译： 一种饮料包装单元，其包括可以饮用或倒出饮料的开口，其中所述开口可由封闭元件密封。 包装单元是平行六面体，并且包括中空的盒状体和封闭元件。 盒状体具有倾斜的角部，在该角部处形成有与身体连接的三角形表面。 管状部分从三角形表面向外延伸并且包括开口。 闭合元件包括大致锥形体，其形状使得当其与盒状体的倾斜角部邻接时，其与主体一起形成平行六面体包装单元。