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1.发明授权Apolipoprotein L-I and/or derivated polypeptide for the treatment of and/or the prevention of diseases induced by trypanosoma 有权用于治疗和/或预防由锥虫病引起的疾病的载脂蛋白L-1和/或衍生多肽公开(公告)号：US07585511B2
公开(公告)日：2009-09-08
申请号：US10523466
申请日：2003-08-04
IPC分类号： A61K39/002
CPC分类号： C12Q1/6893 , A01K2227/101 , A61K38/17 , A61K38/1709 , G01N33/92 , Y02A50/415
摘要： The present invention is related to a composition comprising apolipoprotein L-l, the use of apolipoprotein L-l or a derivated polypeptide for the diagnostic, the treatment and/or the prevention of diseases induced in mammals by Trypanosoma. Another aspect is related to a transgenic non-human mammal comprising a polynucleotide expressing the apolipoprotein L-l or a derivated polypeptide and which is tolerant or resistant to the Trypanosoma infection.
摘要翻译： 本发明涉及包含载脂蛋白L-1，载脂蛋白L-1或衍生多肽用于诊断，治疗和/或预防由锥虫病在哺乳动物中诱导的疾病的组合物的组合物。 另一方面涉及包含表达载脂蛋白L-1或衍生多肽并且对锥虫病感染具有耐受性或抗性的多核苷酸的转基因非人哺乳动物。
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2.发明申请Apolipoprotein l-i and/or derivated polypeptide for the treatment of and/or the prevention of diseases induced by trypanosoma 有权用于治疗和/或预防由锥虫病引起的疾病的载脂蛋白I-1和/或衍生多肽公开(公告)号：US20060263348A1
公开(公告)日：2006-11-23
申请号：US10523466
申请日：2003-08-04
IPC分类号： A61K39/395 , A61K38/17 , C07K14/775
CPC分类号： C12Q1/6893 , A01K2227/101 , A61K38/17 , A61K38/1709 , G01N33/92 , Y02A50/415
摘要： The present invention is related to a composition comprising apolipoprotein L-1, the use of apolipoprotein L-1 or a derivated polypeptide for the diagnostic, the treatment and/or the prevention of diseases induced in mammals by Trypanosoma. Another aspect is related to a transgenic non-human mammal comprising a polynucleotide expressing the apolipoprotein L-1 or a derivated polypeptide and which is tolerant or resistant to the Trypanosoma infection.
摘要翻译： 本发明涉及包含载脂蛋白L-1，载脂蛋白L-1或衍生多肽用于诊断，治疗和/或预防由锥虫病在哺乳动物中诱导的疾病的组合物的组合物。 另一方面涉及包含表达载脂蛋白L-1或衍生多肽并且对锥虫病感染具有耐受性或抗性的多核苷酸的转基因非人哺乳动物。
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