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公开(公告)号：US4629787A
公开(公告)日：1986-12-16
申请号：US394749
申请日：1982-07-02
Applicant: Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
Inventor： Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
IPC: A61K38/00 , C07K5/02 , C07K5/078 , C07D223/10 , A61K31/55
CPC classification number: C07K5/06139 , C07K5/0222 , A61K38/00
Abstract: The invention in its broad aspects relates to caprolactam derivatives which are useful as angiotensin converting enxyme inhibitors and as antihypertensives.
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公开(公告)号：US4396616A
公开(公告)日：1983-08-02
申请号：US299051
申请日：1981-09-04
Applicant: Elbert E. Harris , David Taub , Eugene D. Thorsett
Inventor： Elbert E. Harris , David Taub , Eugene D. Thorsett
IPC: C07D225/02 , A61K31/395 , A61K31/40 , C07D487/08
CPC classification number: C07D225/02
Abstract: Substituted enantholactam dipeptides and derivatives thereof are disclosed which are useful as converting enzyme inhibitors and as antihypertensives.
Abstract translation: 公开了取代的戊内酰胺二肽及其衍生物，其可用作转化酶抑制剂和抗高血压药。
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公开(公告)号：US4587238A
公开(公告)日：1986-05-06
申请号：US396583
申请日：1982-07-09
Applicant: Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
Inventor： Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
IPC: A61K38/00 , C07K5/02 , C07K5/097 , A61K31/33 , C07D225/02
CPC classification number: C07K5/0821 , C07K5/0222 , A61K38/00
Abstract: The invention in its broad aspects relates to caprylolactam derivatives which are useful as angiotensin converting enzyme inhibitors and as antihypertensives.
Abstract translation: 本发明在广泛的方面涉及可用作血管紧张素转换酶抑制剂和抗高血压药物的己内酰胺衍生物。
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公开(公告)号：US4587050A
公开(公告)日：1986-05-06
申请号：US700223
申请日：1985-02-11
Applicant: Elbert E. Harris , Eugene D. Thorsett , Arthur A. Patchett
Inventor： Elbert E. Harris , Eugene D. Thorsett , Arthur A. Patchett
IPC: A61K38/00 , C07K5/02 , C07D225/02
CPC classification number: C07K5/0222 , A61K38/00
Abstract: The invention in its broad aspects relates to enantholactam derivatives which are useful as angiotensin converting enzyme inhibitors and antihypertensives.
Abstract translation: 本发明的广泛方面涉及可用作血管紧张素转换酶抑制剂和抗高血压药物的戊内酰胺衍生物。
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公开(公告)号：US4415496A
公开(公告)日：1983-11-15
申请号：US348811
申请日：1982-02-19
Applicant: Elbert E. Harris , Arthur A. Patchett , Edward W. Tristram , Eugene D. Thorsett , Matthew J. Wyvratt, Jr.
Inventor： Elbert E. Harris , Arthur A. Patchett , Edward W. Tristram , Eugene D. Thorsett , Matthew J. Wyvratt, Jr.
IPC: A61K38/00 , C07D209/48 , C07D513/04 , C07K5/02
CPC classification number: C07D209/48 , C07D513/04 , C07K5/0222 , A61K38/00
Abstract: The invention relates to bicyclic lactams and related compounds which are useful as antihypertensives.
Abstract translation: 本发明涉及可用作抗高血压药物的双环内酰胺类和相关化合物。
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Patent Agency Ranking
公开(公告)号：US4379146A
公开(公告)日：1983-04-05
申请号：US318221
申请日：1981-11-05
Applicant: William J. Greenlee , Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
Inventor： William J. Greenlee , Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
IPC: A61K38/00 , C07F9/572 , C07F9/6539 , C07K5/06 , A61K37/00 , C07C103/52 , C07D277/20
CPC classification number: C07K5/06191 , C07F9/5721 , C07F9/6539 , A61K38/00
Abstract: There are disclosed substituted phosphonamides and related compounds which are useful as converting enzyme inhibitors and as antihypertensives.
Abstract translation: 公开了可用作转化酶抑制剂和抗高血压药物的取代膦酰胺和相关化合物。
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公开(公告)号：US4680392A
公开(公告)日：1987-07-14
申请号：US864234
申请日：1986-05-19
Applicant: Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
Inventor： Elbert E. Harris , Arthur A. Patchett , Eugene D. Thorsett
IPC: A61K38/00 , C07K5/02 , C07K5/078 , C07D223/10 , C07D223/12
CPC classification number: C07K5/06139 , C07K5/0222 , A61K38/00
Abstract: The invention in its broad aspects relates to caprolactam derivatives which are useful as angiotensin converting enxyme inhibitors and as antihypertensives.
Abstract translation: 本发明的广泛方面涉及可用作血管紧张素转化酶抑制剂和抗高血压药的己内酰胺衍生物。
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公开(公告)号：US4409146A
公开(公告)日：1983-10-11
申请号：US394972
申请日：1982-07-02
Applicant: Eugene D. Thorsett , Elbert E. Harris
Inventor： Eugene D. Thorsett , Elbert E. Harris
IPC: C07D223/10
CPC classification number: C07D223/10
Abstract: Substituted caprolactam derivatives are disclosed which are useful as converting enzyme inhibitors and as antihypertensives.
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公开(公告)号：US4316896A
公开(公告)日：1982-02-23
申请号：US940412
申请日：1978-09-07
Applicant: Eugene D. Thorsett , Arthur A. Patchett , Elbert E. Harris , Alan L. Maycock
Inventor： Eugene D. Thorsett , Arthur A. Patchett , Elbert E. Harris , Alan L. Maycock
IPC: A61K31/66 , A61K31/675 , A61K38/00 , A61P9/12 , C07F9/09 , C07F9/165 , C07F9/24 , C07F9/572 , C07F9/6506 , C07F9/653 , C07F9/6539 , C07K5/06 , C07K14/81 , C07D277/20
CPC classification number: C07F9/091 , A61K31/66 , C07F9/1651 , C07F9/2458 , C07F9/5721 , C07F9/6539 , C07K5/06191 , A61K38/00
Abstract: The invention relates to new phosphoryl aminoacid derivatives and related compounds which are useful as antihypertensives.
Abstract translation: 本发明涉及可用作抗高血压药物的新型磷酰基氨基酸衍生物和相关化合物。
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公开(公告)号：US4661479A
公开(公告)日：1987-04-28
申请号：US514219
申请日：1983-07-15
Applicant: Matthew J. Wyvratt, Jr. , Eugene D. Thorsett , Edward W. Tristram , Arthur A. Patchett , Elbert E. Harris
Inventor： Matthew J. Wyvratt, Jr. , Eugene D. Thorsett , Edward W. Tristram , Arthur A. Patchett , Elbert E. Harris
IPC: A61K38/00 , C07D209/48 , C07D513/04 , C07K5/02 , A61K31/55 , A61K35/78
CPC classification number: C07D209/48 , C07D513/04 , C07K5/0222 , A61K38/00
Abstract: This invention relates to bicyclic lactams and derivatives thereof which are useful as converting enzyme inhibitors and as antihypertensives.
Abstract translation: 本发明涉及可用作转化酶抑制剂和抗高血压药物的双环内酰胺及其衍生物。
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