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公开(公告)号：US20110112546A1
公开(公告)日：2011-05-12
申请号：US12846201
申请日：2010-07-29
IPC分类号： A61F11/00
CPC分类号： A61F9/0017 , A61B2090/061 , A61B2090/062 , A61F9/0026 , A61F9/007 , A61F9/00781
摘要： Described herein is a delivery device and methods for delivering an ocular implant into an eye. The delivery device includes a proximal handle portion; a distal delivery portion coupled to a distal end of the handle portion and configured to releasably hold an ocular implant and includes a sheath positioned axially over a guidewire; and a metering system configured to provide visual guidance regarding depth of advancement of an implant positioned on the guidewire into an anatomic region of the eye. Also disclosed is a device and method for loading an implant onto the delivery device.
摘要翻译： 本文描述了用于将眼部植入物递送到眼睛中的递送装置和方法。 输送装置包括近端手柄部分; 远端传送部分，其联接到所述手柄部分的远端并且构造成可释放地保持眼睛植入物并且包括轴向地定位在导丝上的护套; 以及计量系统，其被配置为提供关于定位在所述导丝上的植入物的进展深度到所述眼睛的解剖区域中的视觉指导。 还公开了一种用于将植入物装载到输送装置上的装置和方法。
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公开(公告)号：US08535333B2
公开(公告)日：2013-09-17
申请号：US12846201
申请日：2010-07-29
IPC分类号： A61F11/00
CPC分类号： A61F9/0017 , A61B2090/061 , A61B2090/062 , A61F9/0026 , A61F9/007 , A61F9/00781
摘要： Described herein is a delivery device and methods for delivering an ocular implant into an eye. The delivery device includes a proximal handle portion; a distal delivery portion coupled to a distal end of the handle portion and configured to releasably hold an ocular implant and includes a sheath positioned axially over a guidewire; and a metering system configured to provide visual guidance regarding depth of advancement of an implant positioned on the guidewire into an anatomic region of the eye. Also disclosed is a device and method for loading an implant onto the delivery device.
摘要翻译： 本文描述了用于将眼部植入物递送到眼睛中的递送装置和方法。 输送装置包括近端手柄部分; 远端传送部分，其联接到所述手柄部分的远端并且构造成可释放地保持眼睛植入物并且包括轴向地定位在导丝上的护套; 以及计量系统，其被配置为提供关于定位在所述导丝上的植入物的进展深度到所述眼睛的解剖区域中的视觉指导。 还公开了一种用于将植入物装载到输送装置上的装置和方法。
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公开(公告)号：US08617139B2
公开(公告)日：2013-12-31
申请号：US12492051
申请日：2009-06-25
IPC分类号： A61M1/00
CPC分类号： A61F9/00781 , A61M37/00
摘要： Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging.
摘要翻译： 公开了用于治疗诸如青光眼的眼睛疾病的装置，方法和系统。 这里描述的植入物增强了通过眼睛的正常流出系统的水流量，而极少到没有并发症。 植入物可以可逆地变形为第一形状，例如有利于插入的大致线性形状。 在插入时，植入物可以变形为具有有利于保留在眼睛内的大体非线性形状的第二形状。 该形状还改善了来自前房的流体流动并防止或减少了堵塞。
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公开(公告)号：US20100137981A1
公开(公告)日：2010-06-03
申请号：US12492051
申请日：2009-06-25
CPC分类号： A61F9/00781 , A61M37/00
摘要： Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging.
摘要翻译： 公开了用于治疗诸如青光眼的眼睛疾病的装置，方法和系统。 这里描述的植入物增强了通过眼睛的正常流出系统的水流量，而极少到没有并发症。 植入物可以可逆地变形为第一形状，例如有利于插入的大致线性形状。 在插入时，植入物可以变形为具有有利于保留在眼睛内的大体非线性形状的第二形状。 该形状还改善了来自前房的流体流动并防止或减少了堵塞。
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公开(公告)号：US20100134759A1
公开(公告)日：2010-06-03
申请号：US12492085
申请日：2009-06-25
CPC分类号： A61B3/117 , A61F9/00781
摘要： Described herein is a hand-held gonioscopic imaging system that can be used to continuously display, capture and record images of the iridocorneal angle within the eye during implantation procedures. The system can be used, for example, during device implantation procedures for the treatment of glaucoma such that landmark identification continues during implantation. Intuitive real-time images viewed through the imaging systems described herein appear to the user to move in the same horizontal orientation as the instrument is actually being moved. The systems described herein also provide independent illumination sources for the camera and the surgical microscope that also have independent illumination controls.
摘要翻译： 这里描述的是一种手持式前庭成像系统，其可以用于在植入过程期间连续地显示，捕获和记录眼睛内的虹膜角膜角度的图像。 该系统可用于例如在用于治疗青光眼的装置植入过程期间，使得在植入期间继续进行标记识别。 通过本文描述的成像系统查看的直观的实时图像对用户来说显示为与仪器实际移动时相同的水平方向移动。 本文所述的系统还为摄像机和手术显微镜提供独立的照明源，其也具有独立的照明控制。
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6.发明授权公开(公告)号：US08262726B2
公开(公告)日：2012-09-11
申请号：US12898630
申请日：2010-10-05
IPC分类号： A61F2/14
CPC分类号： A61F9/00781 , A61F2210/0019
摘要： Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.
摘要翻译： 本文描述了用于治疗眼睛状况的装置和方法。 描述了一种眼部植入物，其包括具有形成流动路径的内部内腔的细长构件，与流动通道连通的至少一个流入口以及与流动通路连通的至少一个流出口。 细长构件适于定位在眼睛中，使得至少一个流入端口与前房连通，至少一个流出端口与脉管外空间连通，以在前房和脉管外空间之间提供流体通路，当细长 成员植入眼睛。 细长构件具有赋予细长构件刚性的壁材料。 选择刚度使得在植入之后，细长构件使围绕脉管外空间的眼组织变形，形成帐篷体积。
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7.发明申请OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM 有权具有坚固质量的OCULAR植入物，植入和系统的方法公开(公告)号：US20120016286A1
公开(公告)日：2012-01-19
申请号：US13245802
申请日：2011-09-26
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61F2210/0019
摘要： Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.
摘要翻译： 本文描述了用于治疗眼睛状况的装置和方法。 描述了一种眼部植入物，其包括具有形成流动路径的内部内腔的细长构件，与流动通道连通的至少一个流入口以及与流动通路连通的至少一个流出口。 细长构件适于定位在眼睛中，使得至少一个流入端口与前房连通，至少一个流出端口与脉管外空间连通，以在前房和脉管外空间之间提供流体通路， 成员植入眼睛。 细长构件具有赋予细长构件刚性的壁材料。 选择刚度使得在植入之后，细长构件使围绕脉管外空间的眼组织变形，形成帐篷体积。
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8.发明申请OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM 有权具有坚固质量的OCULAR植入物，植入和系统的方法公开(公告)号：US20140066831A1
公开(公告)日：2014-03-06
申请号：US14071500
申请日：2013-11-04
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F2210/0019
摘要： Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.
摘要翻译： 本文描述了用于治疗眼睛状况的装置和方法。 描述了一种眼部植入物，其包括具有形成流动路径的内部内腔的细长构件，与流动通道连通的至少一个流入口以及与流动通路连通的至少一个流出口。 细长构件适于定位在眼睛中，使得至少一个流入端口与前房连通，至少一个流出端口与脉管外空间连通，以在前房和脉管外空间之间提供流体通路，当细长 成员植入眼睛。 细长构件具有赋予细长构件刚性的壁材料。 选择刚度使得在植入之后，细长构件使围绕脉管外空间的眼组织变形，形成帐篷体积。
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9.发明授权公开(公告)号：US08574294B2
公开(公告)日：2013-11-05
申请号：US12970567
申请日：2010-12-16
IPC分类号： A61F2/14
CPC分类号： A61F9/00781 , A61F2210/0019
摘要： Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.
摘要翻译： 本文描述了用于治疗眼睛状况的装置和方法。 描述了一种眼部植入物，其包括具有形成流动路径的内部内腔的细长构件，与流动通道连通的至少一个流入口以及与流动通路连通的至少一个流出口。 细长构件适于定位在眼睛中，使得至少一个流入端口与前房连通，至少一个流出端口与脉管外空间连通，以在前房和脉管外空间之间提供流体通路，当细长 成员植入眼睛。 细长构件具有赋予细长构件刚性的壁材料。 选择刚度使得在植入之后，细长构件使围绕脉管外空间的眼组织变形，形成帐篷体积。
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公开(公告)号：US08377122B2
公开(公告)日：2013-02-19
申请号：US12694691
申请日：2010-01-27
IPC分类号： A61F2/14
CPC分类号： A61F9/00781 , A61F2210/0019
摘要： Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.
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