公开(公告)号：US20230210993A1

公开(公告)日：2023-07-06

申请号：US18182733

申请日：2023-03-13

Applicant: FUJIFILM Corporation

Inventor： Naoki YAMADA ,  Shun Kaneumi ,  Keiko Suzuki ,  Noriyuki Kasagi ,  Naoto Nakamura

IPC: A61K47/18 ,  A61K47/28 ,  A61K47/24 ,  A61K31/7088 ,  A61K47/10

CPC classification number: A61K47/18 ,  A61K47/28 ,  A61K47/24 ,  A61K31/7088 ,  A61K47/10

Abstract: An object of the present invention is to provide a lipid composition capable of achieving excellent nucleic acid delivery. According to the present invention, there is provided a lipid composition containing a lipid represented by Formula (1) or a salt thereof, a nucleic acid, at least one non-cationic lipid, and a lipid represented by R51-L-(OCH2CH2)n—O-R52 (in the formula, R51 represents a hydrocarbon group having 6 to 30 carbon atoms, L represents —CO— or a single bond, R52 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and n represents an integer of 10 to 150).




In the formula, each symbol means the definition described in the description.