公开(公告)号：US11311623B2

公开(公告)日：2022-04-26

申请号：US16095145

申请日：2016-04-21

Applicant: Fertin Pharma A/S

Inventor： Jesper Thorsen ,  Bjarne Vestbö ,  Birgitte Kringelum Breindal ,  Jesper Neergaard

IPC: A61K9/14 ,  A61K47/58 ,  A61K9/00 ,  A61K9/68 ,  A61K31/465 ,  A61K9/16

Abstract: The present invention relates to a nicotine delivery product comprising, or even consisting essentially of, a population of nicotine-loaded cation exchange resin particles, said population comprises at least 50% (w/w) particles having a size in the range of 90-300 micron which provides an improved nicotine stability to oral dosage forms comprising the nicotine delivery product. The invention furthermore relates to methods of producing the nicotine delivery product and the oral dosage forms and to the use of the nicotine delivery product.

公开(公告)号：US20190134207A1

公开(公告)日：2019-05-09

申请号：US16095145

申请日：2016-04-21

Applicant: Fertin Pharma A/S

Inventor： Jesper Thorsen ,  Bjarne Vestbö ,  Birgitte Kringelum Breindal ,  Jesper Neergaard

IPC: A61K47/58 ,  A61K31/465 ,  A61K9/16 ,  A61K9/00 ,  A61K9/68

Abstract: The present invention relates to a nicotine delivery product comprising, or even consisting essentially of, a population of nicotine-loaded cation exchange resin particles, said population comprises at least 50% (w/w) particles having a size in the range of 90-300 micron which provides an improved nicotine stability to oral dosage forms comprising the nicotine delivery product. The invention furthermore relates to methods of producing the nicotine delivery product and the oral dosage forms and to the use of the nicotine delivery product.