公开(公告)号：US20210070861A1

公开(公告)日：2021-03-11

申请号：US16997577

申请日：2020-08-19

申请人： Five Prime Therapeutics, Inc.

发明人： Yong QUAN ,  Chin-Yi HUANG ,  Harjeet Singh GANDA

IPC分类号： C07K16/28 ,  A61K47/12 ,  A61K47/26 ,  A61K47/22 ,  A61K47/02

摘要： The present disclosure provides pharmaceutical compositions comprising antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4 (and optionally cynomolgus monkey, mouse, and/or rat B7-H4). The present disclosure also prides methods for treating disorders, such as cancer, by administering such pharmaceutical compositions.