公开(公告)号：US20220212193A1

公开(公告)日：2022-07-07

申请号：US17703508

申请日：2022-03-24

申请人： FLUID-SCREEN, INC.

发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

IPC分类号： B01L3/00 ,  B03C5/00 ,  B03C5/02

摘要： An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. A detection method for separating and analyzing a contaminant using the apparatus allows for transporting a test sample having an analyte and a waste product through at least one microfluidic channel; generating dielectrophoretic forces on the test sample as the test sample is transported through the at least one microfluidic channel; trapping the test sample to separate the waste product from the analyte; separating the waste product from the analyte; and sensing, with a sensor, the analyte

公开(公告)号：US11325124B2

公开(公告)日：2022-05-10

申请号：US16728824

申请日：2019-12-27

申请人： FLUID-SCREEN, INC.

发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

IPC分类号： B01L3/00 ,  B03C5/00 ,  B03C5/02 ,  G01N27/414

摘要： An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The electric field is applied to at least one electrode having a plurality of concentric rings or concentric arcs extending radially outwards from a center point, electrically connected to a voltage source such that when voltage is applied to the at least one electrode, the concentric rings or concentric arcs alternate in voltage potential.

公开(公告)号：US11198126B2

公开(公告)日：2021-12-14

申请号：US14582525

申请日：2014-12-24

申请人： Fluid-Screen, Inc.

发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

IPC分类号： B01L3/00 ,  B03C5/00 ,  B03C5/02 ,  G01N27/414

摘要： An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The electric field is applied to at least one electrode having a plurality of concentric rings or concentric arcs extending radially outwards from a center point, electrically connected to a voltage source such that when voltage is applied to the at least one electrode, the concentric rings or concentric arcs alternate in voltage potential.

公开(公告)号：US20210039098A1

公开(公告)日：2021-02-11

申请号：US17071178

申请日：2020-10-15

申请人： Fluid-Screen, Inc.

发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

IPC分类号： B01L3/00 ,  B03C5/00 ,  B03C5/02

摘要： An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The electric field is applied to at least one electrode having a plurality of concentric rings or concentric arcs extending radially outwards from a center point, electrically connected to a voltage source such that when voltage is applied to the at least one electrode, the concentric rings or concentric arcs alternate in voltage potential.

公开(公告)号：US20210039099A1

公开(公告)日：2021-02-11

申请号：US17071202

申请日：2020-10-15

申请人： Fluid-Screen, Inc.

发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

IPC分类号： B01L3/00 ,  B03C5/00 ,  B03C5/02

摘要： An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The electric field is applied to at least one electrode having a plurality of concentric rings or concentric arcs extending radially outwards from a center point, electrically connected to a voltage source such that when voltage is applied to the at least one electrode, the concentric rings or concentric arcs alternate in voltage potential.