公开(公告)号：US20140163222A1

公开(公告)日：2014-06-12

申请号：US13949712

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

公开(公告)号：US20140163005A1

公开(公告)日：2014-06-12

申请号：US13949666

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

公开(公告)号：US20140163007A1

公开(公告)日：2014-06-12

申请号：US13949743

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

公开(公告)号：US20140163004A1

公开(公告)日：2014-06-12

申请号：US13949508

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04 ,  A61K45/06 ,  A61K31/551 ,  A61K31/519 ,  A61K31/5377

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

公开(公告)号：US20140163223A1

公开(公告)日：2014-06-12

申请号：US13949728

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

Abstract translation: 本发明提供吡啶并[2,3-d]嘧啶-7-酮的衍生物。 这些化合物是激酶抑制剂，包括显示抗增殖活性的化合物，包括抗肿瘤细胞，并且可用于治疗包括癌症在内的疾病。

公开(公告)号：US20140163006A1

公开(公告)日：2014-06-12

申请号：US13949690

申请日：2013-07-24

Applicant: Forma Therapeutics, Inc.

Inventor： KRISHNA MURTHI ,  REBECCA CASAUBON ,  ARTHUR F. KLUGE ,  CHASE SMITH ,  JOACHIM VOGT

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61K45/06

Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.