公开(公告)号：US11718875B2

公开(公告)日：2023-08-08

申请号：US16795375

申请日：2020-02-19

申请人： Fred Hutchinson Cancer Center

发明人： J. Lee Nelson ,  Nathalie C. Lambert ,  Vijayakrishna K. Gadi ,  Zhen Yan

IPC分类号： C12Q1/6881 ,  C12Q1/6883

CPC分类号： C12Q1/6881 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158

摘要： The present disclosure provides a panel of nucleic acid molecule primers specific for HLA-specific alleles and other genetic polymorphisms, which are useful for quantitatively amplifying these markers to detect, diagnose, and monitor individuals who have or are at risk of certain disease conditions, such as autoimmune disease, proliferative disease, infectious disease, allograft rejection, or pregnancy-related pathologies.

公开(公告)号：US11718876B2

公开(公告)日：2023-08-08

申请号：US17351135

申请日：2021-06-17

申请人： Fred Hutchinson Cancer Center

发明人： J. Lee Nelson ,  Nathalie C. Lambert ,  Vijayakrishna K. Gadi ,  Zhen Yan

IPC分类号： C12Q1/6881 ,  C12Q1/6883

CPC分类号： C12Q1/6881 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158

摘要： The present disclosure provides a panel of nucleic acid molecule primers specific for HLA-specific alleles and other genetic polymorphisms, which are useful for quantitatively amplifying these markers to detect, diagnose, and monitor individuals who have or are at risk of certain disease conditions, such as autoimmune disease, proliferative disease, infectious disease, allograft rejection, or pregnancy-related pathologies.