公开(公告)号：US20090004295A1

公开(公告)日：2009-01-01

申请号：US12132761

申请日：2008-06-04

申请人： Friedrich W. KUEHNE ,  Michael McGrath ,  Edgar Engleman

发明人： Friedrich W. KUEHNE ,  Michael McGrath ,  Edgar Engleman

IPC分类号： A61K33/20 ,  A61P11/06

CPC分类号： A61K33/40 ,  Y02A50/401

摘要： Methods of using a stabilized chlorite solution to inhibit antigen-specific immune responses are disclosed. The stabilized chlorite solution, when administered to a mammal in need thereof, can prevent the presentation of antigens by antigen presenting cells. The stabilized chlorite solution therefore is useful in treating, inter alia, auto-immune diseases, treating diseases caused by an inappropriate immune response, treating lymphoproliferative disease and in inhibiting rejection in transplant patients.

摘要翻译： 公开了使用稳定的亚氯酸盐溶液来抑制抗原特异性免疫应答的方法。 当向有需要的哺乳动物施用时，稳定的亚氯酸盐溶液可以防止抗原呈递细胞呈递抗原。 因此，稳定的亚氯酸盐溶液可用于治疗特别是自身免疫疾病，治疗由不适当的免疫应答引起的疾病，治疗淋巴增生性疾病和抑制移植患者的排斥反应。