公开(公告)号：US20040028728A1

公开(公告)日：2004-02-12

申请号：US10636731

申请日：2003-08-08

申请人： Fujisawa Pharmaceutical Company, Ltd.

发明人： Jiro Fujisaki ,  Hajime Konno ,  Akihiro Kasai ,  Kazumi Ohtomo

IPC分类号： A61K009/127 ,  A61K031/4745

CPC分类号： A61K9/127 ,  A61K31/407 ,  A61K31/436 ,  A61K31/7042

摘要： The present invention provides a pipecolic acid derivative-containing liposome preparation having has an excellent rapid action capable of coping with an emergent situation such as cerebral infarction. A liposome preparation characterized by comprising, as an active ingredient, a pipecolic acid derivative of the ingredient described in the present specification or a pharmaceutically acceptable salt thereof entrapped into liposomes, wherein lecithin is mainly used as the liposome-forming lipid, said liposome preparation containing no cholesterol as a stabilizer.

摘要翻译： 本发明提供具有能够应对脑梗塞等紧急情况的优异的快速作用的含哌啶酸衍生物的脂质体制剂。 一种脂质体制剂，其特征在于包含作为活性成分的本说明书中描述的成分的哌可酸衍生物或其包埋在脂质体中的药学上可接受的盐，其中卵磷脂主要用作形成脂质体的脂质，所述脂质体制剂含有 没有胆固醇作为稳定剂。