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    Protein having immunogenicity of cedar pollen, polynucleotide encoding the protein, and use thereof
    2.
    发明授权
    Protein having immunogenicity of cedar pollen, polynucleotide encoding the protein, and use thereof 有权
    具有雪松花粉免疫原性的蛋白质，编码蛋白质的多核苷酸及其用途

    公开(公告)号：US09260491B2

    公开(公告)日：2016-02-16

    申请号：US13504636

    申请日：2010-10-28

    申请人： Fumio Takaiwa ,  Hidenori Takagi ,  Yuhya Wakasa ,  Yuji Fujii ,  Tomotaka Shinya ,  Saori Kasahara

    发明人： Fumio Takaiwa ,  Hidenori Takagi ,  Yuhya Wakasa ,  Yuji Fujii ,  Tomotaka Shinya ,  Saori Kasahara

    IPC分类号： A61K39/36 ,  C07K14/415 ,  A61K38/00

    CPC分类号： C07K14/415 ,  A61K38/00 ,  A61K39/36

    摘要： It is an object of the present invention to provide a protein that can successfully treats almost all patients with cedar pollinosis and can be ingested as a food. That is, the present invention provides a protein comprising an amino acid sequence represented by SEQ ID NO:1 or comprising an amino acid sequence having a mutation(s) in said amino acid sequence, and having an immunogenicity of a cedar pollen; a polynucleotide encoding said protein; a vector comprising said polynucleotide; a transformant comprising said polynucleotide or said vector; and intended uses of said protein, said polynucleotide, and said transformant.

    摘要翻译： 本发明的目的是提供一种可以成功地治疗几乎所有患有雪松花粉症的患者的蛋白质，并且可以作为食物摄取。 也就是说，本发明提供了包含由SEQ ID NO：1所示的氨基酸序列或包含在所述氨基酸序列中具有突变并具有雪松花粉免疫原性的氨基酸序列的蛋白质的蛋白质。 编码所述蛋白质的多核苷酸; 包含所述多核苷酸的载体; 包含所述多核苷酸或所述载体的转化体; 和所述蛋白质，所述多核苷酸和所述转化体的预期用途。