公开(公告)号：US20240167091A1

公开(公告)日：2024-05-23

申请号：US18016444

申请日：2021-07-16

申请人： GE Healthcare AS

发明人： Zhoushe ZHAO ,  Hongli LI ,  Yanmei WANG

IPC分类号： C12Q1/6883 ,  C12Q1/6816

CPC分类号： C12Q1/6883 ,  C12Q1/6816 ,  C12Q2600/158

摘要： The present disclosure relates to molecular probes for nucleic acid detection, and preparation and uses thereof. In particular, described herein is a molecular probe for detection of a nucleic acid, comprising, (1) a molecular probe carrier which comprises a cell penetrating peptide and a detectable label coupled to the cell penetrating peptide, and (2) a targeting oligonucleotide, wherein the targeting oligonucleotide is attached to the molecular probe carrier. Also described herein are a method for preparing the molecular probe, a method for detection of a nucleic acid, and a kit for detection of a nucleic acid.