公开(公告)号：US20240400579A1

公开(公告)日：2024-12-05

申请号：US18670520

申请日：2024-05-21

Applicant: GENENTECH, INC. ,  CONVELO THERAPEUTICS, INC.

Inventor： William VERNIER ,  Matthew VOLGRAF ,  Marie-Gabrielle BRAUN ,  Georgette Marie CASTANEDO ,  Paul Anthony GIBBONS ,  James Guy BREITENBUCHER ,  Drew ADAMS ,  Brad LANG

IPC: C07D495/10 ,  A61K31/407 ,  A61K31/4155 ,  A61K31/438 ,  A61K31/4439 ,  A61K31/506

Abstract: The subject matter described herein is directed to myelin-promoting compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for the treatment of myelin-related disorders.