公开(公告)号：US20190264275A1

公开(公告)日：2019-08-29

申请号：US16386888

申请日：2019-04-17

Applicant: GENIA TECHNOLOGIES, INC.

Inventor： Randall W. DAVIS ,  Roger J.A. CHEN

IPC: C12Q1/6869 ,  G01N27/447 ,  C12Q1/6816 ,  G01N33/487 ,  B82Y15/00 ,  C12Q1/6825

Abstract: The present invention relates to a method of using nanopores to obtain sequence information of sample DNAs in ss test DNAs. The method comprises using speed bumps to stall the ss test DNAs in the nanopores at random positions of the ss test DNAs to obtain sequence information of each and every nucleotides of the sample DNAs, and to construct the whole sequences of the sample DNAs. The present invention also relates to identification and/or isolation of test DNAs having desired sequence(s) using nanopore detectors facilitated by speed bump.