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公开(公告)号:US09492565B2
公开(公告)日:2016-11-15
申请号:US14854613
申请日:2015-09-15
Applicant: GENMAB A/S
Inventor: David Satijn , Sandra Verploegen , Wim Bleeker , Steen Lisby , Jan Van De Winkel , Patrick Van Berkel , Paul Parren
IPC: A61K39/395 , A61K47/48 , C07K16/36 , A61K45/06 , C07K16/30
CPC classification number: A61K47/48561 , A61K45/06 , A61K47/6817 , A61K47/6849 , C07K16/30 , C07K16/36 , C07K2317/21 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: Antibody drug conjugates against tissue factor. Also disclosed are pharmaceutical compositions comprising the antibodies and antibody drug conjugates, and therapies and diagnostic methods for using the antibodies and antibody drug conjugates.
Abstract translation: 针对组织因子的抗体药物偶联物。 还公开了包含抗体和抗体药物共轭物的药物组合物,以及使用抗体和抗体药物偶联物的治疗和诊断方法。