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公开(公告)号：US20200247897A1
公开(公告)日：2020-08-06
申请号：US16618722
申请日：2018-06-07
Applicant: GENMAB B.V.
Inventor： Mette Hamborg JENSEN , Lene Schantz HARLOW , Andrew HAGARMAN , Cale HALBLEIB
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present invention relates to formulation of antibodies. The invention relates in particular to pharmaceutical compositions comprising an antibody molecule of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding.
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