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公开(公告)号:US20150337049A1
公开(公告)日:2015-11-26
申请号:US14760157
申请日:2014-01-09
Applicant: GENMAB B.V.
Inventor: Aran Frank LABRIJN , Joyce MEESTERS , Joost J. NEIJSSEN , Edward Norbert VAN DEN BRINK , Janine SCHUURMAN , Paul PARREN
IPC: C07K16/28
Abstract: Described herein are, proteins comprising amino acid substitutions in at least one of a first and a second polypeptide chain. Furthermore, is described the uses and methods related to said proteins.
Abstract translation: 本文描述的是在第一和第二多肽链中的至少一个中包含氨基酸取代的蛋白质。 此外,描述了与所述蛋白质相关的用途和方法。