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公开(公告)号：US12006530B2
公开(公告)日：2024-06-11
申请号：US16075059
申请日：2017-02-03
Applicant: GENOVIS AB
Inventor： Ulrich Von Pawel-Rammingen , Christian Spoerry
CPC classification number: C12Q1/37 , C12N9/641 , G01N33/6854
Abstract: The invention relates to new Streptococcal proteases designated IgdE which display IgG degrading cysteine protease activity. The invention further relates to in vitro methods of cleaving IgG using the described Streptococcal proteases, using the methods to generate Fc and Fab fragments, and using the methods to detect IgG.
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