公开(公告)号：US20190338042A1

公开(公告)日：2019-11-07

申请号：US16455957

申请日：2019-06-28

Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED

Inventor： Christopher John FRANCIS ,  Hua-Xin GAO ,  Yufeng LI ,  Niranjan YANAMANDRA

IPC: C07K16/28 ,  A61K39/395 ,  A61K31/7008 ,  A61K31/7028 ,  C07K16/30 ,  A61K45/06

Abstract: Disclosed herein are combinations of an OX40 modulator and a TLR4 modulator, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combination, including uses in cancer.

公开(公告)号：US20170275371A1

公开(公告)日：2017-09-28

申请号：US15615032

申请日：2017-06-06

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Christopher John FRANCIS ,  Hua-Xin GAO ,  Yufeng LI ,  Niranjan YANAMANDRA

IPC: C07K16/28 ,  A61K31/7028 ,  C07K16/30 ,  A61K39/395

CPC classification number: C07K16/2878 ,  A61K31/7008 ,  A61K31/7028 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/3046 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/75 ,  A61K2300/00

Abstract: Disclosed herein are combinations of an OX40 modulator and a TLR4 modulator, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combination, including uses in cancer.