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公开(公告)号:US20030166031A1
公开(公告)日:2003-09-04
申请号:US10376046
申请日:2003-02-27
IPC分类号: G01N033/53 , G01N033/537 , G01N033/543
CPC分类号: G01N33/6854 , G01N2333/4733 , G01N2333/474 , G01N2410/00
摘要: A solid phase assay is used for detecting antibodies to INGAP104-118 peptide, a 15-amino acid peptide that is the biologically active portion of islet neogenesis associated protein (INGAP). The isotype of the antibodies to INGAP104-118 peptide can be determined. A kit can also be used in the detection of anti-INGAP104-118 antibodies. Endogenous autoantibodies or antibody production during therapeutic treatment of a mammal with INGAP104-118 can be monitored.
摘要翻译: 使用固相测定法检测INGAP104-118肽的抗体,该肽是作为胰岛新生相关蛋白(INGAP)的生物活性部分的15个氨基酸的肽。 可测定INGAP104-118肽抗体的同种型。 一种试剂盒也可用于检测抗INGAP104-118抗体。 可以监测在具有INGAP104-118的哺乳动物治疗期间的内源性自身抗体或抗体产生。
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公开(公告)号:US20020127624A1
公开(公告)日:2002-09-12
申请号:US10036418
申请日:2002-01-07
IPC分类号: G01N033/53 , G01N033/537 , G01N033/543 , C07K016/40
CPC分类号: C07K14/474 , C07K14/4733 , G01N33/6854 , Y10T436/105831 , Y10T436/11
摘要: An antibody is provided which specifically recognizes and binds to INGAP protein. The antibody is used in competitive binding assays for quantitation of INGAP in biological samples. The assay can be performed on a solid support or in a suspension.
摘要翻译: 提供特异性识别和结合INGAP蛋白的抗体。 该抗体用于生物样品中INGAP定量的竞争性结合测定。 该测定可以在固体支持物或悬浮液中进行。
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