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公开(公告)号：US20200075123A1
公开(公告)日：2020-03-05
申请号：US16559465
申请日：2019-09-03
Applicant: GUARDANT HEALTH, INC.
Inventor： Darya CHUDOVA , Mohammad Reza MOKHTARI
Abstract: Methods and systems for improving identification of nucleic acid variants by identifying genetic sequence reads having identical molecular barcodes and sequences among sequence reads from a nucleic acid sequencer, grouping the genetic reads into a family, and processing families comprising split reads to detect the variants in a sample of polynucleotide molecules.
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