公开(公告)号：US20180228751A1

公开(公告)日：2018-08-16

申请号：US15751563

申请日：2016-07-29

申请人： GW PHARMA LIMITED

发明人： Colin STOTT ,  Nicholas JONES ,  Robin WILLIAMS ,  Benjamin WHALLEY

IPC分类号： A61K31/192 ,  A61P25/08 ,  A61K36/185 ,  A61K31/05 ,  A61K45/06

摘要： The present invention relates to the use of a therapeutically effective amount of cannabidiolic acid (CBDA) in the treatment of epilepsy. In one embodiment the CBDA is used in the treatment of generalised seizures, preferably tonic-clonic seizures. Preferably the CBDA used is in the form of a botanical drug substance in which the CBDA content is greater than 60%, and most preferably, it is a highly purified extract of cannabis such that the CBDA is present at greater than 95%, through 96% and 97% to most preferably, greater than 98% of the total extract (w/w) and the other components of the extract are characterised. In particular the cannabinoids tetrahydrocannabinol (THC) or tetrahydrocannabinol acid (THCA) have been substantially removed. Alternatively, the CBDA may be synthetically produced.

公开(公告)号：US20160136127A1

公开(公告)日：2016-05-19

申请号：US14899598

申请日：2014-06-19

申请人： GW PHARMA LIMITED ,  OTSUKA PHARMACEUTICAL CO. LIMITED

发明人： Wai LIU ,  Katherine SCOTT ,  Angus DALGLEISH ,  Marnie DUNCAN ,  Colin STOTT

IPC分类号： A61K31/352 ,  A61K36/185 ,  A61K31/05

CPC分类号： A61K31/352 ,  A61K31/05 ,  A61K36/185 ,  A61P35/00 ,  A61K2300/00

摘要： The present invention relates to the use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer. Preferably the phytocannabinoids used are either tetrahydrocannabinol (THC) and/or cannabidiol (CBD). Preferably the type of cancer to be treated is glioma.

摘要翻译： 本发明涉及植物大麻素用于增加放射敏感性在癌症治疗中的应用。 优选使用的植物大麻素是四氢大麻酚（THC）和/或大麻二酚（CBD）。 优选地，待治疗的癌症的类型是神经胶质瘤。