公开(公告)号：US20130203087A1

公开(公告)日：2013-08-08

申请号：US13810945

申请日：2011-07-18

申请人： Gareth Jones ,  Hans Vordermeier

发明人： Gareth Jones ,  Hans Vordermeier

IPC分类号： G01N33/569

摘要： There is provided a diagnostic reagent useful to determine whether an animal has a tuberculosis infection or has been exposed to a tuberculosis agent, for example a Mycobacterium. The reagent is useful to distinguish between such an animal and an animal which has been vaccinated against a tuberculosis infection.

公开(公告)号：US20130136699A1

公开(公告)日：2013-05-30

申请号：US13643820

申请日：2011-04-28

申请人： Hans Vordermeier ,  Adam Whelan

发明人： Hans Vordermeier ,  Adam Whelan

IPC分类号： A61K49/00

CPC分类号： A61K49/0006 ,  A61K39/00 ,  A61K39/04

摘要： There is provided a skin test diagnostic reagent comprising at least one CFP-10 epitope polypeptide, at least one ESAT-6 epitope polypeptide and at least one Rv3615c epitope polypeptide, the reagent eliciting a positive result when administered in a skin test to an animal infected with Mycobacterium bovis or Mycobacterium tuberculosis. The reagent is useful in that it can be used in a method to determine whether an animal is infected with Mycobacterium bovis or Mycobacterium tuberculosis.

摘要翻译： 提供了包含至少一种CFP-10表位多肽，至少一种ESAT-6表位多肽和至少一种Rv3615c表位多肽的皮肤试验诊断试剂，所述试剂在皮肤试验中给予动物感染时引发阳性结果 与牛分枝杆菌或结核分枝杆菌。 该试剂可用于确定动物是否感染牛分枝杆菌或结核分枝杆菌的方法中。

公开(公告)号：US09050361B2

公开(公告)日：2015-06-09

申请号：US13643820

申请日：2011-04-28

申请人： Hans Vordermeier ,  Adam Whelan

发明人： Hans Vordermeier ,  Adam Whelan

IPC分类号： A61K39/04 ,  A61K39/00 ,  A61K49/00

CPC分类号： A61K49/0006 ,  A61K39/00 ,  A61K39/04

摘要： There is provided a skin test diagnostic reagent comprising at least one CFP-10 epitope polypeptide, at least one ESAT-6 epitope polypeptide and at least one Rv3615c epitope polypeptide, the reagent eliciting a positive result when administered in a skin test to an animal infected with Mycobacterium bovis or Mycobacterium tuberculosis. The reagent is useful in that it can be used in a method to determine whether an animal is infected with Mycobacterium bovis or Mycobacterium tuberculosis.

摘要翻译： 提供了包含至少一种CFP-10表位多肽，至少一种ESAT-6表位多肽和至少一种Rv3615c表位多肽的皮肤试验诊断试剂，所述试剂在皮肤试验中给予动物感染时引发阳性结果 与牛分枝杆菌或结核分枝杆菌。 该试剂可用于确定动物是否感染牛分枝杆菌或结核分枝杆菌的方法中。