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公开(公告)号:US20140005218A1
公开(公告)日:2014-01-02
申请号:US13964975
申请日:2013-08-12
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , Beuford A. Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , Beuford A. Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号: A61K9/00 , A61K31/485
CPC分类号: A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要: The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
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公开(公告)号:US08475832B2
公开(公告)日:2013-07-02
申请号:US12537571
申请日:2009-08-07
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
CPC分类号: A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要: The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
摘要翻译: 本发明涉及用于治疗麻醉药物依赖性的产品和方法。 本发明更具体地涉及自支持剂型,其提供用于治疗麻醉依赖性的活性剂,同时提供剂型的足够的颊粘连。
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公开(公告)号:US20110033542A1
公开(公告)日:2011-02-10
申请号:US12537580
申请日:2009-08-07
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号: A61K9/00 , A61K31/485
CPC分类号: A61K9/006 , A61K9/0056 , A61K9/7007 , A61K31/485 , A61K47/10 , A61K47/12
摘要: The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The invention more particularly relates to self-supporting dosage forms which provide an active agent while providing sufficient buccal adhesion of the dosage form. Further, the present invention provides a dosage form which is useful in reducing the likelihood of diversion abuse of the active agent.
摘要翻译: 本发明涉及治疗患者各种症状的产品和方法,包括治疗患者所遭受的疼痛。 本发明更具体地涉及提供活性剂同时提供剂型的足够的颊粘附的自支撑剂型。 此外,本发明提供了可用于降低活性剂的转移滥用可能性的剂型。
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公开(公告)号:US20110033541A1
公开(公告)日:2011-02-10
申请号:US12537571
申请日:2009-08-07
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号: A61K9/10 , A61K31/4355
CPC分类号: A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要: The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
摘要翻译: 本发明涉及用于治疗麻醉药物依赖性的产品和方法。 本发明更具体地涉及自支持剂型,其提供用于治疗麻醉依赖性的活性剂,同时提供剂型的足够的颊粘连。
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公开(公告)号:US20130281481A1
公开(公告)日:2013-10-24
申请号:US13923749
申请日:2013-06-21
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号: A61K31/485
CPC分类号: A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要: The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
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公开(公告)号:US20130035378A1
公开(公告)日:2013-02-07
申请号:US13588267
申请日:2012-08-17
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
IPC分类号: A61K31/365 , A61P3/04
CPC分类号: A61K9/7007 , A61K31/365 , A61K47/26 , A61K47/34 , A61K47/38
摘要: The present invention includes a pharmaceutical-based film system which includes various small-scale forms of pharmaceutically active agents, including tetrahydrolipstatin, in a film base. Such forms include nanoparticles, microparticles, and combinations thereof. Methods of producing such film and providing a dosage of the pharmaceutical in a film are also provided
摘要翻译: 本发明包括药物基膜系统,其在膜基质中包括各种小规模形式的药物活性剂,包括四氢脂肪抑制素。 这些形式包括纳米颗粒,微粒及其组合。 还提供了制备这种膜并提供药物在膜中的剂量的方法
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公开(公告)号:US08663696B2
公开(公告)日:2014-03-04
申请号:US13588267
申请日:2012-08-17
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
IPC分类号: A61K9/14 , A61K9/70 , A61K38/00 , A61K31/335
CPC分类号: A61K9/7007 , A61K31/365 , A61K47/26 , A61K47/34 , A61K47/38
摘要: The present invention includes a pharmaceutical-based film system which includes various small-scale forms of pharmaceutically active agents, including tetrahydrolipstatin, in a film base. Such forms include nanoparticles, microparticles, and combinations thereof. Methods of producing such film and providing a dosage of the pharmaceutical in a film are also provided.
摘要翻译: 本发明包括药物基膜系统,其在膜基质中包括各种小规模形式的药物活性剂,包括四氢脂肪抑制素。 这些形式包括纳米颗粒,微粒及其组合。 还提供了制备这种膜并提供药物在膜中的剂量的方法。
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公开(公告)号:US08298583B2
公开(公告)日:2012-10-30
申请号:US11975584
申请日:2007-10-19
申请人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
发明人: Garry L. Myers , Samuel D. Hilbert , Bill J. Boone
IPC分类号: A61K9/14 , A61K9/70 , A61K38/00 , A61K31/335
CPC分类号: A61K9/7007 , A61K31/365 , A61K47/26 , A61K47/34 , A61K47/38
摘要: The present invention includes a pharmaceutical-based film system which includes various small-scale forms of pharmaceutically active agents, including tetrahydrolipstatin, in a film base. Such forms include nanoparticles, microparticles, and combinations thereof. Methods of producing such film and providing a dosage of the pharmaceutical in a film are also provided.
摘要翻译: 本发明包括药物基膜系统,其在膜基质中包括各种小规模形式的药物活性剂,包括四氢脂肪抑制素。 这些形式包括纳米颗粒,微粒及其组合。 还提供了制备这种膜并提供药物在膜中的剂量的方法。
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公开(公告)号:US20080233174A1
公开(公告)日:2008-09-25
申请号:US12013989
申请日:2008-01-14
申请人: Garry L. Myers , Bill J. Boone , Samuel D. Hilbert
发明人: Garry L. Myers , Bill J. Boone , Samuel D. Hilbert
CPC分类号: A61K9/006 , A61K9/7007 , A61K47/10
摘要: This invention relates to films incorporating high amounts of pharmaceutical agents and methods for the preparation of the same. Moreover, the invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译: 本发明涉及含有大量药剂的薄膜及其制备方法。 此外,本发明涉及其制备的膜产品及其方法,其证明非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地,膜含有每单位面积膜的活性剂药物和/或化妆品活性剂不超过10%变化的药物和/或化妆品活性剂。
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