公开(公告)号：US20210396755A1

公开(公告)日：2021-12-23

申请号：US17220888

申请日：2021-04-01

申请人： Genalyte, Inc.

发明人： Lawrence Cary Gunn, III ,  Richard Deane Hockett, JR. ,  Sasi Mudumba

IPC分类号： G01N33/569 ,  B01L3/00 ,  G01N21/39

摘要： Disclosed herein are methods of performing multiplexed serological immunoassays to detect multiple antigens in parallel to determine if a patient has an infection or an immune disorder. Use of multiple antigens in parallel increases specificity and/or sensitivity towards assaying the infection or immune disorder. The infection may be a viral infection such as a SARS-CoV-2 viral infection, a variant of a SARS-CoV-2 viral infection, or a non-SARS-CoV-2 coronavirus infection. Also disclosed herein are methods of performing the multiplexed serological immunoassays on an optical ring resonator substrate. Also disclosed herein are methods of detecting antibodies specific for an antigen that belong to more than one immunoglobulin type.