公开(公告)号：US11865177B2

公开(公告)日：2024-01-09

申请号：US16914100

申请日：2020-06-26

Applicant: Genentech, Inc.

Inventor： Anthony Tomlinson ,  Barthelemy Luc Demeule ,  Isidro Angelo Eleazar Zarraga

IPC: A61K39/395 ,  A61K9/08 ,  A61K9/19 ,  A61K47/22

CPC classification number: A61K39/39591 ,  A61K9/08 ,  A61K9/19 ,  A61K47/22

Abstract: The present disclosure provides liquid formulations comprising polypeptides and surfactants. In particular, it discloses a liquid formulation comprising a polypeptide and a surfactant, wherein at least about 70% (wt %) of the surfactant are isosorbide polyoxyethylene (POE) fatty acid esters. The invention also provides methods for making such liquid formulations, articles of manufacture comprising such liquid formulations and methods of treating a patient with such liquid formulations.