公开(公告)号：US20150366930A1

公开(公告)日：2015-12-24

申请号：US14604556

申请日：2015-01-23

Applicant: Genentech, Inc.

Inventor： Weilan YE ,  Leon H. PARKER ,  Christopher W. WILSON

IPC: A61K38/02 ,  C12N15/113

CPC classification number: A61K38/02 ,  A61K31/00 ,  A61K31/7105 ,  C12N15/113

Abstract: The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.

Abstract translation: 本发明提供了使用RASIP1激动剂和拮抗剂调节血管屏障功能并调节新血管形成以及治疗相关疾病的方法。