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公开(公告)号:US12205386B2
公开(公告)日:2025-01-21
申请号:US17841610
申请日:2022-06-15
Applicant: Genentech, Inc.
Inventor: Zheng Li , Mandy Man Chu Yim , Bibi Ephraim , Dat Tran , Xinyu Liu , David Shaw
Abstract: A method includes, by a computing system, receiving a querying image depicting a sampling area, processing the querying image using a single cluster detection model to identify one or more regions of the querying image depicting a cluster in the sampling area, processing the one or more regions using a cluster verification deep-learning model to determine whether each depicted cluster is a cell cluster, and determining that exactly one of the identified one or more regions depicts a cluster that is a cell cluster. The method further includes processing the region depicting the cell cluster using a morphology deep-learning model to determine that there is only one cell in the cell cluster and to determine that die morphology of the cell is acceptable.