公开(公告)号：US20210332142A1

公开(公告)日：2021-10-28

申请号：US17208292

申请日：2021-03-22

Applicant: Genentech, Inc.

Inventor： Minhong YAN ,  Gu ZHANG ,  Nicholas John AGARD ,  Danielle Marie DICARA ,  Philip E. HASS ,  Julie Q. HANG ,  Erin L. CHRISTENSEN ,  Robert Paul MORSE ,  Sarah SANOWAR ,  Vittal SHIVVA

IPC: C07K16/28 ,  A61K47/68 ,  A61K47/60 ,  A61K45/06 ,  A61K39/395 ,  A61K9/00 ,  A61P27/02

Abstract: The invention provides Tie-2 antibodies and fragments thereof and conjugates and methods of using the same.

公开(公告)号：US20150250874A1

公开(公告)日：2015-09-10

申请号：US14720671

申请日：2015-05-22

Applicant: Genentech, Inc.

Inventor： Minhong YAN ,  Gu ZHANG

IPC: A61K39/395 ,  C07K19/00 ,  C07K16/40

CPC classification number: A61K39/3955 ,  A61K39/39558 ,  A61K2039/505 ,  C07K16/40 ,  C07K19/00 ,  C07K2319/30 ,  A61K2300/00

Abstract: Disclosed herein are methods and compositions for treating disorders associated with angiogenesis or lymphangiogenesis using ALK-1 antagonists.