公开(公告)号：US20180216196A1

公开(公告)日：2018-08-02

申请号：US15821407

申请日：2017-11-22

Applicant: Genentech, Inc.

Inventor： Edward KADEL ,  Marcin KOWANETZ ,  Kimberly WALTER

IPC: C12Q1/6886 ,  C07K16/28 ,  A61P35/00

CPC classification number: C12Q1/6886 ,  A61P35/00 ,  C07K16/2827 ,  C07K2317/56 ,  C07K2317/76 ,  C12Q2600/106 ,  C12Q2600/154

Abstract: This invention provides methods for the treatment of cancer in subjects having medium or low methylation level in the PD-L1 promoter region. Also provided are related kits and articles of manufacture.