公开(公告)号：US20210322426A1

公开(公告)日：2021-10-21

申请号：US17223105

申请日：2021-04-06

Applicant: Genentech, Inc.

Inventor： Susan Greene ,  Stephanie Joo ,  Jennifer Schutzman

IPC: A61K31/5377 ,  A61K31/4745 ,  A61K31/4439 ,  A61K31/553 ,  A61K31/501 ,  A61K31/519 ,  A61K31/444 ,  A61K31/437 ,  A61K31/427 ,  A61K31/565 ,  A61K31/155 ,  A61K31/506 ,  A61K31/337 ,  A61K31/675 ,  A61K31/704 ,  A61K31/4196 ,  A61K31/7068 ,  A61K31/138 ,  A61K31/395 ,  A61P35/00

Abstract: Described herein are methods of treating PIK3CA-mutant cancer patients by administering metformin and a PI3K alpha inhibitor.

公开(公告)号：US20210252013A1

公开(公告)日：2021-08-19

申请号：US17156381

申请日：2021-01-22

Applicant: Genentech, Inc.

Inventor： Susan Greene ,  Stephanie Joo ,  Jennifer Schutzman

IPC: A61K31/553 ,  A61K45/06 ,  A61P35/00 ,  A61K31/519 ,  A61K31/565

Abstract: Described herein are methods of treating PIK3CA-mutant cancer patients by administering metformin and a PI3K inhibitor, GDC-0077.

公开(公告)号：US20250127796A1

公开(公告)日：2025-04-24

申请号：US18668774

申请日：2024-05-20

Applicant: Genentech, Inc.

Inventor： Susan Greene ,  Stephanie Joo ,  Jennifer Schutzman

IPC: A61K31/553 ,  A61K31/519 ,  A61K31/565 ,  A61K45/06 ,  A61P35/00

Abstract: Described herein are methods of treating PIK3CA-mutant cancer patients by administering metformin and a PI3K inhibitor, GDC-0077.