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公开(公告)号:US20130084287A1
公开(公告)日:2013-04-04
申请号:US13630363
申请日:2012-09-28
Applicant: Genentech, Inc.
Inventor: David Shames , Thomas M. Holcomb , Kimberly Walter
IPC: C12Q1/68
CPC classification number: C12Q1/6827 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/154
Abstract: The present invention provides methods for determining epithelial and mesenchymal phenotype of tumors and predicting whether tumor growth will be sensitive or resistant to treatment with an EGFR inhibitor.
Abstract translation: 本发明提供了用于确定肿瘤的上皮和间质表型的方法,并且预测肿瘤生长是否对EGFR抑制剂治疗敏感或具有抗性。