公开(公告)号：US20190338231A1

公开(公告)日：2019-11-07

申请号：US16474316

申请日：2017-12-22

Applicant: General Electric Company

Inventor： Manoj Ramakrishna ,  Anoop Bhargav ,  Umesh Pai

IPC: C12M1/00 ,  C12M1/36 ,  C12M3/06

Abstract: Disclosed is a cell culture system comprising a first cell culture bioreactor system (10) for culturing cells to a predetermined cell density or quantity, the system including a bioreactor volume (20), a process controller (30), process control devices (32) which provide inputs (16) for the culture volume and culture parameter measurement devices (14), wherein the process controller is operable according to plural control program steps to control the process devices to provide inputs for a suitable cell culture environment in the bioreactor volume, and is further operable according to control program steps modified by feedback values from the culture parameter measurement devices, and comprises a memory (36) operable to record data indicative of the progress of the control program steps. Failure of the system can be rectified by moving the bioreactor volume to another similar system which has access to data indicative of any incomplete program steps which steps may have been modified by feedback from the measurement devices.