公开(公告)号：US20140221249A1

公开(公告)日：2014-08-07

申请号：US13759701

申请日：2013-02-05

Applicant: Genia Technologies, Inc.

Inventor： Roger J.A. Chen ,  David J. Fullager

IPC: G01N27/327

CPC classification number: G01N33/48721

Abstract: A method of analyzing molecules using a nanopore array including a plurality of cells included on a chip is disclosed. Nanopores are caused to be formed in at least a portion of the plurality of the cells. A first physical measurement of the nanopores is evaluated. It is determined whether to cause the molecules to interact with the nanopores. At least a portion of the nanopores is caused to interact with the molecules. A second physical measurement of the nanopores that indicates a property of the molecules is evaluated. It is determined whether to cause the nanopores to be reformed so that the cells may be reused to interact with additional molecules.

Abstract translation: 公开了一种使用包括在芯片上的多个单元的纳米孔阵列来分析分子的方法。 导致在多个电池的至少一部分中形成纳米孔。 评估纳米孔的第一物理测量。 确定是否使分子与纳米孔相互作用。 导致至少一部分纳米孔与分子相互作用。 评估表明分子性质的纳米孔的第二物理测量。 确定是否使纳米孔被重整，使得细胞可以重新用于与另外的分子相互作用。