公开(公告)号：US12173329B2

公开(公告)日：2024-12-24

申请号：US18355990

申请日：2023-07-20

Applicant: Genomatica, Inc.

Inventor： Mathew Rude ,  Na Trinh ,  Andreas Schirmer ,  Jacob Gano

IPC: C12N9/02 ,  C12P7/04 ,  C12P7/24 ,  C12P7/6409

Abstract: The disclosure relates to acyl-ACP reductase (AAR) enzyme variants that result in improved fatty aldehyde and fatty alcohol production when expressed in recombinant host cells. The disclosure further relates to methods of making and using such AAR variants for the production of fatty alcohol compositions having particular characteristics.

公开(公告)号：US11130944B2

公开(公告)日：2021-09-28

申请号：US16272303

申请日：2019-02-11

Applicant: Genomatica, Inc.

Inventor： Mathew Rude ,  Na Trinh ,  Andreas Schirmer ,  Jacob Gano

IPC: C12N9/02 ,  C12P7/64 ,  C12P7/24 ,  C12P7/04

Abstract: The disclosure relates to acyl-ACP reductase (AAR) enzyme variants that result in improved fatty aldehyde and fatty alcohol production when expressed in recombinant host cells. The disclosure further relates to methods of making and using such AAR variants for the production of fatty alcohol compositions having particular characteristics.