公开(公告)号：US20050272954A1

公开(公告)日：2005-12-08

申请号：US11092333

申请日：2005-03-29

Applicant: George Kraus ,  Jaehoon Bae

Inventor： George Kraus ,  Jaehoon Bae

IPC: C07C231/10 ,  C07C233/09

CPC classification number: C07C233/09

Abstract: A method of synthesizing diacetylenic amides is described. The key steps of the invention include the reaction of an aldehyde with the monoanion of a diacetylene and the reductive removal of a propargylic alcohol. The invention offers the first known method of synthesizing diacetylenic amides that are naturally isolated from Echinacea through a direct and flexible route.

Abstract translation: 描述了合成二炔酰胺的方法。 本发明的关键步骤包括醛与二乙炔的单阴离子的反应以及炔丙醇的还原性除去。 本发明提供了通过直接和柔性的途径合成天然分离自紫锥菊的二乙酰基酰胺的第一已知方法。

公开(公告)号：US20070173543A1

公开(公告)日：2007-07-26

申请号：US11275756

申请日：2006-01-26

Applicant: George Kraus ,  Yi Yuan

Inventor： George Kraus ,  Yi Yuan

IPC: A61K31/353 ,  C07D493/14

CPC classification number: C07D493/18

Abstract: A method for preparing A-type procyanidins is provided by reacting flavylium salts with catechins and analogs thereof, under anhydrous conditions in alcohol.

Abstract translation: 通过在无水条件下在醇中将黄烷鎓盐与儿茶素类及其类似物反应来提供A型原花青素的方法。