专利检索 ap:("George Phillip Vlasuk" OR "Patrick Eric Hugo Stanssens" OR "Joris Hilda Lieven Messens" OR "Marc Jozef Lauwereys" OR "Yves Rene n Laroche" OR "Laurent Stephane Jespers" OR "Yannick George Jozef Gansemans" OR "Matthew Moyle" OR "Peter W. Bergum") AND inv:"Yves Rene n Laroche" 第 1 页

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发明授权
Nematode-extracted anticoagulant protein 失效

公开(公告)号：US5866542A

公开(公告)日：1999-02-02

申请号：US486397

申请日：1995-06-05

申请人： George Phillip Vlasuk , Patrick Eric Hugo Stanssens , Joris Hilda Lieven Messens , Marc Jozef Lauwereys , Yves Rene n Laroche , Laurent Stephane Jespers , Yannick George Jozef Gansemans , Matthew Moyle , Peter W. Bergum

发明人： George Phillip Vlasuk , Patrick Eric Hugo Stanssens , Joris Hilda Lieven Messens , Marc Jozef Lauwereys , Yves Rene n Laroche , Laurent Stephane Jespers , Yannick George Jozef Gansemans , Matthew Moyle , Peter W. Bergum

IPC分类号： A61K38/00 , A61P7/02 , C07K14/81 , A61K38/57

CPC分类号： C07K14/811 , A61K38/00

摘要： Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.