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公开(公告)号:US5597900A
公开(公告)日:1997-01-28
申请号:US376536
申请日:1995-01-20
申请人: Gerald Hammond , Hung V. Le , T. L. Nagabhushan , Paul Reichert , Paul P. Trotta
发明人: Gerald Hammond , Hung V. Le , T. L. Nagabhushan , Paul Reichert , Paul P. Trotta
CPC分类号: C07K14/5406 , A61K38/00
摘要: A process for crystallizing recombinant human interleukin 4 (rhulL-4) from a solution containing a sulfate or citrate salt is described. The crystalline form is suitable for x-ray diffraction and has wide applications in several pharmaceutical processes including purification, formulation and manufacturing.
摘要翻译: 描述了从含有硫酸盐或柠檬酸盐的溶液中结晶重组人白细胞介素4(rhILL-4)的方法。 结晶形式适用于x射线衍射,并且在多种药物方法中广泛应用,包括纯化,配制和制造。