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1.
公开(公告)号:US20070191299A1
公开(公告)日:2007-08-16
申请号:US11696782
申请日:2007-04-05
申请人: Gerhard Seeman , Gunter Cichon
发明人: Gerhard Seeman , Gunter Cichon
IPC分类号: A61K48/00 , A61K31/277 , A61K31/4439 , A61K31/42
CPC分类号: A61K31/275 , A61K31/42
摘要: Prolongation of the expression of transgenic proteins by immunomodulating treatment The invention relates to the use of one or more immunosuppressants for the production of a pharmaceutical for increasing the tolerance of a mammal to transgenic cells, and to a process for identifying immunosuppressants suitable for this. By the use of pharmaceuticals of this type, the production of the transgenic expression product is markedly prolonged even after discontinuing the immunosuppressant treatment.
摘要翻译: 通过免疫调节处理延长转基因蛋白质的表达本发明涉及一种或多种免疫抑制剂用于生产用于增加哺乳动物对转基因细胞的耐受性的药物的用途,以及用于鉴定适用于此的哺乳动物的免疫抑制剂的方法。 通过使用这种药物,转基因表达产物的生产即使在停止免疫抑制剂治疗后也显着延长。