专利检索 ap:("Geron Corporation") AND inv:"Stephen Kelsey" 第 1 页

1.

发明授权
Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms 有权
标题翻译：使用端粒酶抑制剂治疗骨髓增生性疾病和骨髓增生性肿瘤

公开(公告)号：US09375485B2

公开(公告)日：2016-06-28

申请号：US13841711

申请日：2013-03-15

申请人： Geron Corporation

发明人： Monic J. Stuart , Stephen Kelsey

IPC分类号： A61K47/48 , A61K49/04 , B82Y5/00

CPC分类号： C12N15/1135 , A61K47/543 , A61K47/549 , A61K49/0423 , B82Y5/00 , C12N2320/30

摘要： Provided herein are methods for reducing neoplastic progenitor cell proliferation and alleviating symptoms associated in individuals diagnosed with or thought to have Essential Thrombocythemia (ET). Also provided herein are methods for using telomerase inhibitors for maintaining blood platelet counts at relatively normal ranges in the blood of individuals diagnosed with or suspected of having ET.

摘要翻译： 本文提供了减少肿瘤祖细胞增殖并减轻与诊断患有或被认为具有基础性血小板增多症（ET））的个体相关的症状的方法。本文还提供了使用端粒酶抑制剂在被诊断患有或怀疑具有ET的个体的血液中在相对正常范围内维持血小板计数的方法。